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2023-03-15. Schizophrenia pinpointed as a key factor in heat deaths. [https://www.science.org/content/article/schizophrenia-pinpointed-key-factor-heat-deaths] By Warren Cornwall, Science. Excerpt: ...more than 600 people died from the heat in British Columbia, as temperatures topped 40°C for days, shattering records in a region better known for temperatures usually half as high. Now, new research has zeroed in on one of the hardest hit groups: people with schizophrenia. Epidemiologists combing through provincial health records found that, overall, those with mental health conditions seemed to have an elevated risk of a heat-related death. That was most severe for people with schizophrenia—a 200% increase compared with typical summers. ...schizophrenia can affect the brain’s hypothalamus, which helps regulate temperature through sweating and shivering. Some antipsychotic medications can raise body temperature, which can have deadly effects when coupled with extreme heat. The disease affects people’s ability to make reasoned decisions or sense when they are ill. People with schizophrenia tend to have other conditions tied to heat-related illness, such as diabetes. Finally, schizophrenia is associated with isolation and homelessness, which puts people at risk when temperatures rise.... 

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